/* ============================================================
   PureLife Pharma — SynBD program site
   Design system. Cobalt / navy / leaf. Newsreader + Inter.
   ============================================================ */

:root{
  --cobalt:#1b4ddb;        /* SynBD brief blue */
  --cobalt-deep:#1740b4;
  --navy:#0c1d52;          /* ink on light */
  --navy-900:#081541;      /* deep section bg */
  --ink:#10193a;
  --slate:#54608a;         /* muted body */
  --leaf:#6fae8f;          /* box leaf accent */
  --leaf-deep:#3f8769;
  --mist:#eef2fb;          /* pale panel */
  --mist-2:#f6f8fd;
  --line:#dbe3f4;
  --white:#ffffff;
  --gold:#c9a86a;          /* family gold whisper (ThreeWoods) */
  --wrap:1180px;
  --r:14px;
  --ease:cubic-bezier(.2,.7,.2,1);
}

*{box-sizing:border-box}
html{scroll-behavior:smooth}
body{
  margin:0;color:var(--ink);background:var(--white);
  font-family:"Inter",system-ui,-apple-system,Segoe UI,Roboto,sans-serif;
  font-size:17px;line-height:1.7;-webkit-font-smoothing:antialiased;
  text-rendering:optimizeLegibility;
}
h1,h2,h3,h4{font-family:"Newsreader",Georgia,serif;font-weight:500;line-height:1.12;color:var(--navy);margin:0 0 .5em}
h1{font-size:clamp(2.5rem,5.6vw,4.4rem);letter-spacing:-.01em}
h2{font-size:clamp(1.9rem,3.6vw,2.9rem);letter-spacing:-.01em}
h3{font-size:1.35rem;line-height:1.25}
p{margin:0 0 1.1em}
em{font-style:italic;color:var(--cobalt)}
a{color:var(--cobalt);text-decoration:none}
a:hover{text-decoration:underline}
img{max-width:100%;display:block}
.wrap{width:100%;max-width:var(--wrap);margin:0 auto;padding:0 28px}
section{padding:104px 0}
.skip-link{position:absolute;left:-9999px;top:0;background:var(--navy);color:#fff;padding:10px 16px;z-index:200}
.skip-link:focus{left:8px;top:8px}

.eyebrow{
  display:inline-flex;align-items:center;gap:12px;font-family:"Inter";font-weight:600;font-size:.74rem;
  letter-spacing:.2em;text-transform:uppercase;color:var(--cobalt);margin-bottom:18px;
}
.eyebrow:before{content:"";width:26px;height:1px;background:currentColor;display:inline-block;flex:none}
.eyebrow.on-dark{color:var(--gold)}
.section-head{max-width:760px;margin-bottom:56px}
.section-head p{font-size:1.18rem;color:var(--slate)}

/* ---------- buttons ---------- */
.btn{
  display:inline-block;background:var(--cobalt);color:#fff;font-weight:600;font-size:.95rem;
  padding:14px 26px;border-radius:999px;border:1.5px solid var(--cobalt);
  transition:transform .25s var(--ease),background .25s,box-shadow .25s;white-space:nowrap;
}
.btn:hover{background:var(--cobalt-deep);text-decoration:none;transform:translateY(-2px);box-shadow:0 12px 30px -12px rgba(27,77,219,.55)}
.btn.ghost{background:transparent;color:var(--navy);border-color:var(--line)}
.btn.ghost:hover{background:var(--mist);border-color:var(--cobalt);box-shadow:none;color:var(--navy)}
.btn.on-dark{background:#fff;color:var(--navy);border-color:#fff}
.btn.on-dark:hover{background:#eaf0ff;color:var(--navy)}
.btn.ghost.on-dark{background:transparent;color:#fff;border-color:rgba(255,255,255,.4)}
.btn.ghost.on-dark:hover{background:rgba(255,255,255,.08);border-color:#fff}
.link-arrow{font-weight:600;color:var(--cobalt)}
.link-arrow:after{content:" →";transition:margin .2s var(--ease)}
.link-arrow:hover{text-decoration:none}
.link-arrow:hover:after{margin-left:5px}

/* ---------- header ---------- */
header.site{position:sticky;top:0;z-index:120;background:rgba(255,255,255,.86);backdrop-filter:blur(12px);border-bottom:1px solid var(--line)}
.nav{display:flex;align-items:center;justify-content:space-between;height:72px}
.logo{display:flex;align-items:center;gap:11px}
.logo:hover{text-decoration:none}
.logo svg{width:30px;height:30px;flex:none}
.logo img.mark{height:34px;width:auto;flex:none}
.logo-word{font-family:"Newsreader",serif;font-size:1.32rem;color:var(--navy);line-height:1}
.logo-word b{font-weight:600}
.logo-word span{color:var(--cobalt);font-weight:600}
.logo-word.synbd{font-family:"Inter",sans-serif;font-weight:700;font-size:1.42rem;letter-spacing:-.01em;color:var(--navy)}
.entity-line{font-size:.8rem;color:#7184b6;margin-top:6px;line-height:1.5}
.foot-entity{display:flex;align-items:center;gap:12px;margin:18px 0 6px}
.foot-entity img{height:34px;width:auto;border-radius:6px}
.nav-links{display:flex;gap:30px;list-style:none;margin:0;padding:0}
.nav-links a{color:var(--navy);font-size:.93rem;font-weight:500}
.nav-links a:hover{color:var(--cobalt);text-decoration:none}
.nav .btn{padding:10px 20px}
.menu-toggle{display:none;background:none;border:0;font-size:1.5rem;color:var(--navy);cursor:pointer}

/* ---------- hero ---------- */
.hero{position:relative;overflow:hidden;background:linear-gradient(160deg,#0e2a78 0%,var(--cobalt) 55%,#2a5ce8 100%);color:#fff;padding:120px 0 110px}
.hero:before{content:"";position:absolute;inset:0;background:
  radial-gradient(circle at 82% 18%,rgba(255,255,255,.16),transparent 42%),
  radial-gradient(circle at 12% 92%,rgba(111,174,143,.22),transparent 45%);}
.hero .wrap{position:relative;z-index:2;max-width:920px}
.hero h1{color:#fff}
.hero h1 em{color:#f0cf86;font-style:italic}  /* gold-on-dark, family accent — visible on cobalt */
.hero .lede{font-size:1.3rem;line-height:1.6;color:#dbe6ff;max-width:660px;margin:24px 0 34px}
.hero-actions{display:flex;gap:16px;flex-wrap:wrap;align-items:center}
.hero-mol{position:absolute;right:-60px;top:50%;transform:translateY(-50%);width:520px;height:520px;opacity:.5;z-index:1}
.hero-mol circle,.hero-mol line{stroke:rgba(255,255,255,.5);fill:none}

/* ---------- credibility strip ---------- */
.cred{background:var(--navy-900);color:#fff}
.cred .row{display:flex;flex-wrap:wrap;gap:14px 48px;justify-content:space-between;align-items:center;padding:30px 0}
.cred .item{display:flex;flex-direction:column}
.cred .item b{font-family:"Newsreader",serif;font-size:1.7rem;font-weight:500;color:#fff;line-height:1}
.cred .item span{font-size:.82rem;letter-spacing:.04em;color:#9fb2e6;margin-top:4px}

/* ---------- problem ---------- */
.problem{background:var(--mist-2)}
.stat-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:26px;margin-top:46px}
.stat{background:#fff;border:1px solid var(--line);border-radius:var(--r);padding:32px 28px}
.stat b{display:block;font-family:"Newsreader",serif;font-size:2.6rem;color:var(--cobalt);line-height:1;margin-bottom:8px}
.stat p{margin:0;color:var(--slate);font-size:.98rem}

/* ---------- split / platform ---------- */
.split{display:grid;grid-template-columns:1.05fr .95fr;gap:64px;align-items:center}
.platform-visual{background:linear-gradient(155deg,#11329a,#1b4ddb);border-radius:20px;padding:54px 40px;text-align:center;position:relative;overflow:hidden}
.platform-visual:before{content:"";position:absolute;inset:0;background:radial-gradient(circle at 70% 20%,rgba(255,255,255,.14),transparent 50%)}
.platform-visual img{position:relative;margin:0 auto;filter:drop-shadow(0 26px 40px rgba(0,0,0,.34));max-width:340px}
.platform-visual .cap{position:relative;color:#cfe;font-size:.8rem;letter-spacing:.14em;text-transform:uppercase;margin-top:26px;color:#bcd0ff}
.feature-list{list-style:none;margin:30px 0 0;padding:0}
.feature-list li{position:relative;padding:0 0 18px 34px;color:var(--ink)}
.feature-list li:before{content:"";position:absolute;left:0;top:8px;width:16px;height:16px;border-radius:50%;background:var(--leaf);box-shadow:0 0 0 4px rgba(111,174,143,.2)}
.feature-list li b{color:var(--navy)}

/* ---------- why grid ---------- */
.why{background:var(--navy-900);color:#fff}
.why h2{color:#fff}
.why .section-head p{color:#b9c8ee}
.why-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:24px;margin-top:14px}
.why-card{background:rgba(255,255,255,.05);border:1px solid rgba(255,255,255,.12);border-radius:var(--r);padding:30px 26px;transition:transform .3s var(--ease),background .3s}
.why-card:hover{transform:translateY(-4px);background:rgba(255,255,255,.08)}
.why-card .n{font-family:"Newsreader",serif;color:#7fa6ff;font-size:1rem;letter-spacing:.1em;margin-bottom:14px}
.why-card h3{color:#fff;font-size:1.2rem;margin-bottom:10px}
.why-card p{color:#c2cff0;font-size:.95rem;margin:0}

/* ---------- trial / program ---------- */
.program .split{gap:54px}
.endpoints{display:grid;grid-template-columns:repeat(2,1fr);gap:18px;margin-top:30px}
.endpoint{background:var(--mist);border-radius:12px;padding:22px 22px;border-left:3px solid var(--cobalt)}
.endpoint b{display:block;font-weight:700;color:var(--navy);font-size:.95rem;margin-bottom:4px}
.endpoint span{font-size:.86rem;color:var(--slate)}
.milestone{display:flex;gap:16px;align-items:flex-start;padding:16px 0;border-bottom:1px solid var(--line)}
.milestone:last-child{border-bottom:0}
.milestone .dot{flex:none;width:12px;height:12px;border-radius:50%;background:var(--leaf);margin-top:7px}
.milestone p{margin:0;color:var(--ink)}
.milestone p span{display:block;color:var(--slate);font-size:.92rem}

/* ---------- pipeline / program status ---------- */
.pipeline{border:1px solid var(--line);border-radius:var(--r);overflow:hidden;margin-top:14px;background:#fff}
.pipe-head,.pipe-row{display:grid;grid-template-columns:1.3fr 1.6fr 1fr 1.1fr;gap:18px;align-items:center;padding:18px 26px}
.pipe-head{background:var(--navy-900);color:#fff;font-size:.74rem;letter-spacing:.14em;text-transform:uppercase;font-weight:600}
.pipe-row{border-top:1px solid var(--line)}
.pipe-row .asset{font-family:"Newsreader",serif;font-size:1.25rem;color:var(--navy)}
.pipe-row .ind{color:var(--ink);font-weight:500}
.pipe-row .ind span{display:block;color:var(--slate);font-size:.85rem;font-weight:400}
.phasebar{display:flex;gap:5px;align-items:center}
.phasebar i{height:7px;border-radius:4px;flex:1;background:var(--line)}
.phasebar i.on{background:var(--cobalt)}
.phasebar i.now{background:var(--leaf)}
.pipe-row .stat-tag{font-size:.8rem;font-weight:600;color:var(--leaf-deep);background:rgba(111,174,143,.14);border-radius:999px;padding:6px 12px;justify-self:start;text-align:center}
.pipe-note{font-size:.8rem;color:var(--slate);margin-top:12px}

/* ---------- precedent / validation strip ---------- */
.precedent{background:#fff;border:1px solid var(--line);border-left:3px solid var(--gold);border-radius:var(--r);padding:34px 36px;display:grid;grid-template-columns:auto 1fr;gap:28px;align-items:center;margin-top:8px}
.precedent .mark{font-family:"Newsreader",serif;font-size:2.4rem;color:var(--navy);line-height:1;white-space:nowrap}
.precedent .mark span{display:block;font-family:"Inter";font-size:.72rem;letter-spacing:.14em;text-transform:uppercase;color:var(--gold);font-weight:600;margin-top:8px}
.precedent p{margin:0;color:var(--ink)}
@media (max-width:720px){.pipe-head{display:none}.pipe-row{grid-template-columns:1fr;gap:10px;padding:20px}.precedent{grid-template-columns:1fr;gap:16px}}

/* ---------- hero lead-program chip ---------- */
.lead-prog{display:inline-flex;align-items:center;gap:12px;background:rgba(255,255,255,.1);border:1px solid rgba(255,255,255,.22);border-radius:12px;padding:14px 20px;margin:6px 0 30px;color:#eaf0ff;font-size:.98rem;max-width:600px}
.lead-prog b{color:#f0cf86;font-weight:700;white-space:nowrap}

/* ---------- snapshot dashboard ---------- */
.snapshot{display:grid;grid-template-columns:repeat(4,1fr);gap:1px;background:var(--line);border:1px solid var(--line);border-radius:var(--r);overflow:hidden;margin-top:18px}
.snap{background:#fff;padding:22px 22px}
.snap .k{display:block;font-size:.7rem;letter-spacing:.13em;text-transform:uppercase;color:var(--slate);font-weight:600;margin-bottom:9px}
.snap .v{font-family:"Newsreader",serif;font-size:1.32rem;color:var(--navy);line-height:1.12}
.snap .v small{display:block;font-family:"Inter";font-size:.74rem;color:var(--slate);font-weight:400;margin-top:3px}
.snap .v.good{color:var(--leaf-deep)}
@media(max-width:760px){.snapshot{grid-template-columns:repeat(2,1fr)}}
@media(max-width:420px){.snapshot{grid-template-columns:1fr}}

/* ---------- why matters cards ---------- */
.matters-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:24px;margin-top:14px}
.matter{background:#fff;border:1px solid var(--line);border-radius:var(--r);padding:32px 30px}
.matter .big{font-family:"Newsreader",serif;font-size:2.2rem;color:var(--cobalt);line-height:1;display:block;margin-bottom:10px}
.matter h3{font-size:1.18rem;margin-bottom:8px}
.matter p{margin:0;color:var(--slate);font-size:.97rem}
@media(max-width:760px){.matters-grid{grid-template-columns:1fr}}

/* ---------- why-grid 4-up modifier ---------- */
.why-grid.four{grid-template-columns:repeat(4,1fr)}
@media(max-width:980px){.why-grid.four{grid-template-columns:repeat(2,1fr)}}
@media(max-width:560px){.why-grid.four{grid-template-columns:1fr}}

/* ---------- roadmap ---------- */
.roadmap{display:grid;grid-template-columns:repeat(6,1fr);gap:0;margin-top:32px}
.rm-step{padding:0 14px;border-left:1px solid var(--line)}
.rm-step:first-child{border-left:0;padding-left:0}
.rm-step .bar{height:6px;border-radius:4px;background:var(--line);margin-bottom:16px}
.rm-step.done .bar{background:var(--cobalt)}
.rm-step.now .bar{background:var(--leaf)}
.rm-step .tag{font-size:.66rem;letter-spacing:.1em;text-transform:uppercase;font-weight:700;color:var(--leaf-deep);display:block;margin-bottom:7px;min-height:13px}
.rm-step.done .tag{color:var(--cobalt)}
.rm-step h4{font-family:"Inter";font-size:.95rem;font-weight:700;color:var(--navy);margin-bottom:4px}
.rm-step p{font-size:.82rem;color:var(--slate);margin:0}
@media(max-width:820px){.roadmap{grid-template-columns:1fr;gap:14px}.rm-step{border-left:3px solid var(--line);border-top:0;padding:6px 0 6px 18px}.rm-step:first-child{padding-left:18px}.rm-step .bar{display:none}.rm-step.done{border-color:var(--cobalt)}.rm-step.now{border-color:var(--leaf)}}

/* ---------- platform potential (dark) ---------- */
.plat-grid{display:grid;grid-template-columns:repeat(5,1fr);gap:18px;margin-top:26px}
.plat{background:rgba(255,255,255,.05);border:1px solid rgba(255,255,255,.14);border-radius:12px;padding:24px 18px;text-align:center;transition:transform .3s var(--ease),background .3s}
.plat:hover{transform:translateY(-3px);background:rgba(255,255,255,.08)}
.plat b{display:block;font-family:"Newsreader",serif;color:#fff;font-size:1.06rem;margin-bottom:6px}
.plat span{font-size:.72rem;letter-spacing:.08em;text-transform:uppercase;font-weight:600}
.plat.lead{border-color:rgba(240,207,134,.5)}
.plat.lead span{color:#f0cf86}
.plat.exp span{color:#9db0e0}
@media(max-width:820px){.plat-grid{grid-template-columns:repeat(2,1fr)}}

/* ---------- partners ---------- */
.partner-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:24px;margin-top:16px}
.partner{background:#fff;border:1px solid var(--line);border-radius:var(--r);padding:30px 28px}
.partner .ic{width:42px;height:42px;border-radius:10px;background:var(--mist);display:flex;align-items:center;justify-content:center;margin-bottom:16px}
.partner .ic svg{width:22px;height:22px;stroke:var(--cobalt);fill:none;stroke-width:1.6}
.partner h3{font-size:1.12rem;margin-bottom:8px}
.partner p{margin:0;color:var(--slate);font-size:.94rem}
@media(max-width:760px){.partner-grid{grid-template-columns:1fr}}

/* ---------- team ---------- */
.team{background:var(--mist-2)}
.team-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:30px;margin-top:18px}
.member{background:#fff;border:1px solid var(--line);border-radius:var(--r);padding:30px 26px;transition:box-shadow .3s var(--ease),transform .3s}
.member:hover{box-shadow:0 22px 50px -28px rgba(12,29,82,.4);transform:translateY(-3px)}
.member img{width:88px;height:88px;border-radius:50%;object-fit:cover;object-position:top center;margin-bottom:18px;background:var(--mist);border:3px solid #fff;box-shadow:0 0 0 1px var(--line)}
.member h3{font-size:1.12rem;margin-bottom:2px}
.member .role{color:var(--cobalt);font-weight:600;font-size:.85rem;margin-bottom:12px}
.member p{font-size:.9rem;color:var(--slate);margin:0}

/* ---------- investor CTA band ---------- */
.invest{background:linear-gradient(155deg,#0e2a78,var(--cobalt));color:#fff;text-align:center}
.invest h2{color:#fff}
.invest .wrap{max-width:760px}
.invest p{color:#d7e3ff;font-size:1.15rem}
.invest .hero-actions{justify-content:center;margin-top:14px}

/* ---------- contact ---------- */
.contact-grid{display:grid;grid-template-columns:1fr 1fr;gap:54px;align-items:start}
.contact-card{background:var(--mist);border-radius:var(--r);padding:30px;margin-bottom:18px}
.contact-card b{color:var(--navy)}
.field{margin-bottom:16px}
.field label{display:block;font-size:.82rem;font-weight:600;color:var(--navy);margin-bottom:6px}
.field input,.field textarea,.field select{width:100%;padding:13px 15px;border:1px solid var(--line);border-radius:10px;font:inherit;font-size:.95rem;background:#fff;color:var(--ink)}
.field input:focus,.field textarea:focus,.field select:focus{outline:none;border-color:var(--cobalt);box-shadow:0 0 0 3px rgba(27,77,219,.12)}
.field textarea{min-height:120px;resize:vertical}
.form-note{font-size:.8rem;color:var(--slate);margin-top:6px}

/* ---------- footer ---------- */
footer.site{background:var(--navy-900);color:#aebbe0;padding:64px 0 30px;font-size:.92rem}
footer.site .cols{display:grid;grid-template-columns:1.4fr 1fr 1fr;gap:40px;margin-bottom:40px}
footer.site h4{color:#fff;font-family:"Inter";font-size:.78rem;letter-spacing:.14em;text-transform:uppercase;font-weight:600;margin-bottom:16px}
footer.site a{color:#aebbe0}
footer.site a:hover{color:#fff}
footer.site ul{list-style:none;margin:0;padding:0}
footer.site li{margin-bottom:10px}
.foot-logo{display:flex;align-items:center;gap:10px;margin-bottom:14px}
.foot-logo svg{width:26px;height:26px}
.foot-logo span{font-family:"Newsreader",serif;font-size:1.15rem;color:#fff}
.disclaimer{border-top:1px solid rgba(255,255,255,.12);padding-top:22px;font-size:.78rem;line-height:1.65;color:#8294c4;max-width:none}
.disclaimer p{margin:0 0 10px}
.legal-row{display:flex;justify-content:space-between;flex-wrap:wrap;gap:10px;margin-top:18px;font-size:.8rem;color:#7184b6}

/* ---------- reveal animation ---------- */
.reveal{opacity:0;transform:translateY(22px);transition:opacity .7s var(--ease),transform .7s var(--ease)}
.reveal.in{opacity:1;transform:none}
.reveal.d1{transition-delay:.08s}.reveal.d2{transition-delay:.16s}.reveal.d3{transition-delay:.24s}
@media (prefers-reduced-motion:reduce){.reveal{opacity:1;transform:none;transition:none}}

/* ---------- pill / badge ---------- */
.pill{display:inline-flex;align-items:center;gap:7px;background:var(--mist);border:1px solid var(--line);color:var(--navy);font-size:.8rem;font-weight:600;padding:7px 14px;border-radius:999px;margin:0 8px 8px 0}
.pill .d{width:8px;height:8px;border-radius:50%;background:var(--leaf)}

/* ---------- subpage hero ---------- */
.page-hero{background:linear-gradient(160deg,#0e2a78,var(--cobalt));color:#fff;padding:84px 0 70px}
.page-hero h1{color:#fff;font-size:clamp(2.1rem,4.4vw,3.2rem)}
.page-hero p{color:#d7e3ff;max-width:620px;font-size:1.15rem;margin:0}
.prose{max-width:760px}
.prose h2{font-size:1.5rem;margin-top:40px}
.prose h3{font-size:1.12rem;margin-top:26px}
.prose ul{padding-left:20px}
.prose li{margin-bottom:8px}
.back-link{display:inline-block;margin-top:36px;font-weight:600}

/* ---------- responsive ---------- */
@media (max-width:920px){
  section{padding:76px 0}
  .nav-links,.nav>.btn{display:none}
  .nav-links.open{display:flex;position:absolute;top:72px;left:0;right:0;flex-direction:column;gap:0;background:#fff;border-bottom:1px solid var(--line);padding:8px 0}
  .nav-links.open li{padding:0 28px}
  .nav-links.open a{display:block;padding:14px 0;border-bottom:1px solid var(--mist)}
  .menu-toggle{display:block}
  .split,.contact-grid{grid-template-columns:1fr;gap:40px}
  .stat-grid,.why-grid,.team-grid{grid-template-columns:1fr}
  .endpoints{grid-template-columns:1fr}
  .hero-mol{display:none}
  footer.site .cols{grid-template-columns:1fr;gap:28px}
  .platform-visual{order:-1}
}
@media (max-width:560px){
  .stat-grid{gap:16px}
  .cred .row{gap:18px 28px}
  .cred .item b{font-size:1.4rem}
}